Best Powder Probiotic Supplements of 2025

Elisa Drew
Last Updated: Jan 8, 2025

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Powder probiotic supplements are a great way to improve gut health and support the immune system. These supplements are easy to take and can be mixed into food or drinks for convenience. They contain beneficial bacteria that help to balance the microbiome and improve digestion. Powder probiotic supplements are available in a variety of flavors and formulations to suit individual needs. They are a popular choice for those looking to improve their overall health and wellbeing.

At a Glance: Our Top Picks

#TOP 1
NOW Probiotic-10™ Powder, 50 Billion, 2-Ounce
ftb score rating icon9.9
#TOP 2
Garden of Life Probiotics Fitbiotic Weight Management Powder
ftb score rating icon9.8
#TOP 3
Florastor Kids Probiotic Supplement
ftb score rating icon9.6

Top 10 Powder Probiotic Supplements

#TOP 1

NOW Probiotic-10™ Powder, 50 Billion, 2-Ounce

2927
NOW Supplements, Probiotic-10™ Powder, 50 Billion, with 10 Probiotic Strains, Strain Verified, 2-Ounce
ftb score rating icon9.9
FTB Score

Probiotic-10 offers 10 clinically validated strains of probiotics that can naturally colonize the human GI tract, supporting healthy digestion, intestinal lining, motility, and detoxification process. The powder form makes it easy to mix with your favorite beverage or food. NOW Supplements, the family-owned and operated company since 1968, ensures the quality of the product with NPA A-rated GMP certification. Note that heat or sunlight may damage the product, so it's recommended to be available during delivery.

What We Like
Offers 10 probiotic strains that are known to naturally colonize the human GI tract
Utilizes clinically validated strains for healthy immune system function
Helps maintain the integrity of the intestinal lining, support proper intestinal motility, and participate in the detoxification process
#TOP 2

Garden of Life Probiotics Fitbiotic Weight Management Powder

Garden of Life Dr. Formulated Probiotics Fitbiotic Weight Management Powder 50 Billion CFU & Fiber, Organic & Non-GMO Digestive Gut Health Supplement, 3 Oz, Pack of 20
ftb score rating icon9.8
FTB Score

Garden of Life Fitbiotic Probiotic is a daily dietary supplement designed to support digestion and weight management. With a potent blend of 50 billion CFU, it includes clinically studied strains for weight loss support, as well as acidophilus for digestive health and immune system support. This probiotic also contains 4g of organic fiber to promote satiety, helping you feel fuller for longer. The addition of organic Acacia fiber acts as a prebiotic, nourishing the growth of beneficial bacteria in the gut. With 20 one daily packets, this shelf-stable probiotic is convenient and requires no refrigeration. It is certified organic, dairy-free, gluten-free, soy-free, vegetarian, and sugar-free, making it suitable for a variety of dietary needs.

What We Like
Digestion support
Weight management
Prebiotic and probiotic supplement

Florastor Kids Probiotic Supplement

68268
Florastor Kids Dual Action Probiotic Supplement, Strengthens Kids' Digestive & Immune Health, 20 Easy-to Mix Powder Sticks, Packaging May Vary
ftb score rating icon9.6
FTB Score

Florastor Kids Daily Probiotic Supplement is an unflavored powder that is perfect for children aged 2 months and up. It is formulated to help your child maintain healthy digestion and support their immune system. The probiotic is resistant to 16 of the most commonly used oral antibiotics and does not require refrigeration. Florastor is the number one probiotic in its class worldwide, using a unique and effective probiotic strain that has been researched for over 65 years. This probiotic supplement is vegetarian, gluten-free, titanium dioxide-free, and appropriate for lactose intolerance.

What We Like
Resistant to 16 common oral antibiotics
Supports digestive and immune system health
Number one probiotic in its class worldwide
Vegetarian, gluten-free, titanium dioxide-free, and appropriate for lactose intolerance

GoLive Probiotics & Prebiotics TANGERINE TURMERIC Synbiotic Powder

P207
Tangerine Turmeric
GoLive Probiotics & Prebiotics TANGERINE TURMERIC Synbiotic Powder, Probiotics + Prebiotics for Women, Men & Kids+15 Billion CFUs,15 Clinical Strains for Immune & Digestive Health.10's Pack
ftb score rating icon9.4
FTB Score

GoLive Probiotics & Prebiotics TANGERINE TURMERIC Synbiotic Powder promotes gut and digestive health, contains 15+ billion CFUs and 15 clinically tested, documented probiotic strains, and is delivered in patented, foil-sealed packaging that ensures live and active cultures. It is suitable for men, women, and kids and can be easily mixed into food and drinks. The product is clean, gluten-free, vegan, and contains no artificial colors, flavors, sweeteners, or preservatives.

What We Like
Promotes gut and digestive health
Contains 15+ billion CFUs and 15 clinically tested, documented probiotic strains
Delivered in patented, foil-sealed packaging that ensures live and active cultures
Suitable for men, women, and kids, and can be easily mixed into food and drinks
Clean, gluten-free, vegan, and contains no artificial colors, flavors, sweeteners, or preservatives
#TOP 5

Youtheory Spore Probiotic Powder

SPBPA.00721
White
Youtheory Spore Probiotic Powder - Vegan Gut Health Supplement for Men & Women* - 6 Billion CFU - Dairy, Soy & Gluten Free - 3.45 oz
ftb score rating icon9.4
FTB Score

Youtheory Probiotic Powder is the next evolution in probiotics. Its spore-based formula resists stomach acid, ensuring maximum effectiveness as it reaches your intestinal tract. The protective shell around each spore safeguards the probiotic from external factors. With a potent 6 billion CFU, prebiotics FOS and XOS, it offers tummy TLC by providing essential food for beneficial bacteria. This product helps support gut health, balance mood, boost energy, and improve sleep quality. Plus, it's vegan, dairy-free, soy-free, and gluten-free, making it a healthy choice for you.

What We Like
Spore-based formula
Protective shell for effectiveness
6 billion CFU potency
#TOP 6

Lovebug Toddler & Kids Probiotics

Lovebug Toddler Probiotics - Organic Probiotic for Kids & Toddler Constipation Relief, Stomach Discomfort and Softer Bowel Movements, Clear Dissolvable Powder, Ages 12 Months to 4 Year Olds - 30 Pack
ftb score rating icon9.4
FTB Score

Lovebug Probiotics offers a specialized blend of 8 probiotic strains tailored for toddlers and young children aged 12 months to 4 years. The formulation aims to address digestive upsets, diarrhea, and constipation common in this age group. By providing 15 billion active cultures, including Lactobacillus GG, it supports digestive and immune health. Lovebug Probiotics is non-GMO, gluten-free, and free from artificial colors or flavors, ensuring a safe option for your child's well-being.

What We Like
Specialized probiotic strains
Supports digestive + immune health
Non-GMO & allergen-free
#TOP 7

Garden of Life Probiotic Supplement for Digestive and Gut Health

Garden of Life Whole Food Primal Defense HSO Probiotic Dietary Supplement for Digestive and Gut Health, Vegetarian Powder, 2.85 oz
ftb score rating icon9.4
FTB Score

Primal Defense by Garden of Life is a vegetarian probiotic supplement that supports digestive and gut health. With lactobacillus acidophilus, bifidobacteria, and other strains, it maximizes the benefits of a healthy diet, boosts nutrient absorption, and promotes regular bowel movements. The formula contains a unique whole food blend with Homeostatic Soil Organisms (HSOs), which are probiotics that are abundant in soil untouched by chemicals. The proprietary Colon Care Blend supports colon health, and the 12 hardy beneficial strains provide immune system support. This gluten-free, dairy-free, and vegetarian powder is a great way to replenish valuable probiotics that are no longer present in our pasteurized, irradiated, and disinfected food.

What We Like
Contains unique HSOs not found in other probiotics
Includes 12 hardy beneficial strains for immune system health
Supports digestive health, nutrient absorption, and regular bowel movements
Vegetarian, gluten-free, and dairy-free
Shelf-stable formula
#TOP 8

GoLive Probiotics & Prebiotics Powder

0895070002159
Flavorless
GoLive Probiotics & Prebiotics FLAVORLESS/SUGARLESS Synbiotic Powder, Probiotics + Prebiotics for Women, Men & Kids +15 Billion CFUs, 15 Clinical Strains for Immune & Digestive Health. 5's pack
ftb score rating icon9.2
FTB Score

GoLive Probiotics Powder is designed to support your gut and digestive health. The unique fiber blend nourishes beneficial bacteria, helping to maintain a healthy balance in your digestive system. With over 15 billion CFUs from 15 clinically tested probiotic strains, this product promotes better digestive and immune function. The patented packaging ensures that the probiotics remain viable and effective, even under various temperatures. It’s convenient for everyone—men, women, and kids—because it easily mixes into any food or drink, making it simple to incorporate into your daily routine.

What We Like
Supports gut health
Clinically tested strains
Convenient packaging
Easy to mix
No refrigeration needed
#TOP 9

VSL#3 Probiotics Powder for Digestive Health

VSL#3
745749017802
VSL#3 Probiotics for Digestive Health, Probiotic Powder, Medical Food for Gut Health Support in Women & Men, High Potency, Multi-Strain, Live Refrigerated Probiotics, 450 Billion CFUs, 30 Pack
ftb score rating icon9.2
FTB Score

VSL#3 Probiotics is a high-potency probiotic powder designed to support digestive health for both men and women. It features eight different strains of beneficial bacteria, which work together to enhance gut health. These probiotics are stored and shipped under refrigerated conditions to maintain their effectiveness, ensuring you receive live cultures that are ready to work for you. As the top-recommended brand by gastroenterologists, VSL#3 stands out as a medical food, offering a higher standard than typical dietary supplements. Plus, it's gentle on your stomach, being both lactose-free and gluten-free, making it easy to incorporate into your daily routine.

What We Like
High potency with 450 billion CFUs
Multi-strain formula for enhanced effectiveness
Refrigerated shipping for optimal viability
Recommended by gastroenterologists
#TOP 10

Vitamatic Lactobacillus Probiotic Powder

810078475309
Vitamatic Lactobacillus Acidophilus Probiotic Powder - Digestive Health Support - 100 Gram (3.5 OZ) - 100 Servings
ftb score rating icon9.0
FTB Score

Vitamatic Probiotic Powder is designed to support your digestive and immune health with its powerful formula. Each serving delivers 100 billion live cultures, ensuring you receive high potency for optimal results. This non-GMO and gluten-free powder is free from common allergens such as soy, yeast, and wheat, making it suitable for various dietary needs. The product undergoes rigorous laboratory testing to guarantee superior quality and trustworthiness, giving you peace of mind with every scoop. Enjoy the convenience of a pure powder that fits seamlessly into your daily routine.

What We Like
High potency per serving
Supports digestive health
Non-GMO and gluten-free
Laboratory tested quality
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Are powdered probiotics effective?

Powdered probiotics can be effective, especially for those who have difficulty swallowing pills or capsules. However, without a protective coating, the bacteria in powdered form are more vulnerable to stomach acid.

2. Is it better to take probiotic pills or powder?

Probiotics in capsules, tablets, and yogurt tend to survive stomach acids better than powders or liquids. Certain types of bacteria, such as Lactobacillus, Bifidobacterium, and Enterococci, are more resistant to stomach acid. Therefore, probiotic pills or capsules may be a better choice for ensuring the survival of beneficial bacteria.

3. Can you get probiotics in powder form?

Yes, probiotics are available in powder form, along with other forms like capsules and fermented foods such as yogurt or kimchi. Powdered probiotics can be convenient for those who prefer this form or need it for specific purposes.

4. Do probiotics flatten your stomach?

Certain probiotics, such as Lactobacillus rhamnosus and L. gasseri, have been shown to reduce belly fat. Probiotics support healthy digestive function, which can help reduce bloating in the stomach. A healthy gut can also lower inflammation in the body, making it easier to maintain a healthy weight.

5. What are the benefits of powdered probiotics?

Powdered probiotics offer several benefits, including optimizing gut function by balancing the bacteria in the digestive system, reducing symptoms of digestive disorders, reducing the frequency of diarrhea, maintaining and improving gut integrity, reducing gas and bloating, and even improving mood and reducing stress.

6. Should I take probiotics in the morning or at night?

Taking probiotics in the morning is often recommended as stomach acid production is usually at its lowest during that time. This allows the probiotics to reach the small and large intestines before breakfast. However, the best time to take probiotics can vary depending on individual preferences, as long as it is taken consistently at the same time each day.

7. How long does it take for probiotic powder to work?

When taking a high-quality and multi-strain probiotic supplement, initial improvements and health benefits can be noticed within the first 1-2 weeks. Individual sensitivities may vary, but many people report feeling a difference after a few days of consistent probiotic use.

Editor's Notes

During our powder probiotic supplement research, we found 24 powder probiotic supplement products and shortlisted 10 quality products. We collected and analyzed 60,182 customer reviews through our big data system to write the powder probiotic supplements list. We found that most customers choose powder probiotic supplements with an average price of $26.10.

The powder probiotic supplements are available for purchase. We have researched hundreds of brands and picked the top brands of powder probiotic supplements, including NOW Foods, Garden of Life, Florastor, GoLive, Youtheory. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.