Best Acidophilus Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 16, 2025

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Acidophilus supplements are a popular form of probiotics that can help maintain a healthy gut flora. These supplements contain live bacteria that are naturally present in the digestive system and can help improve digestion and boost the immune system. Acidophilus supplements are available in various forms such as capsules, tablets, and powders, and can be found in most health food stores or online. They are often recommended for people who have taken antibiotics or suffer from digestive issues such as bloating, gas, and diarrhea. It is always advisable to consult a healthcare professional before starting any new dietary supplement.

At a Glance: Our Top Picks

Nature’s Bounty Acidophilus Probiotic Cover#TOP 1
Nature’s Bounty Acidophilus Probiotic
ftb score rating icon9.9
NOW Acidophilus Two Billion Cover#TOP 2
NOW Acidophilus Two Billion
ftb score rating icon9.8
NOW Supplements Probiotic Capsules Cover#TOP 3
NOW Supplements Probiotic Capsules
ftb score rating icon9.6

Top 10 Acidophilus Supplements

#TOP 1

Nature’s Bounty Acidophilus Probiotic

Nature’s Bounty Acidophilus Probiotic Cover
Nature's Bounty Acidophilus Probiotic, Daily Probiotic Supplement, Supports Digestive Health, Twin Pack, 100 Count (Pack of 2)
ftb score rating icon9.9
FTB Score

Nature's Bounty Acidophilus Probiotic is a stomach friendly supplement that provides friendly bacteria for the digestive system. It contains over 100 million active Lactobacillus Acidophilus and is free of artificial colors, flavors, and sweeteners. Customers have reported positive results in their digestion and have found the product to be worth the money. However, some customers have noted that they have to take two tablets per day instead of one.

What We Like
Improves digestive health
Easy to swallow capsules
Gentle on the stomach
Long-lasting supply
Reputable brand quality
#TOP 2

NOW Acidophilus Two Billion

2905
Light Cream
NOW Acidophilus Two Billion Cover
NOW Foods Supplements, Acidophilus, Two Billion, Strain Verified, Healthy Intestinal Flora*, 100 Veg Capsules
ftb score rating icon9.8
FTB Score

NOW Acidophilus Two Billion is a probiotic supplement that promotes a healthy intestinal flora and positive probiotic balance. It contains Lactobacillus acidophilus, which is a beneficial bacteria commonly found in the intestinal tract. This probiotic has been used for years to support digestive health. By taking 1 to 4 capsules daily, you can maintain a healthy balance of gut bacteria. NOW Acidophilus Two Billion is strain verified, ensuring the quality and identity of the probiotic strains. It is also non-GMO, soy-free, vegan/vegetarian, and gluten-free, making it suitable for various dietary preferences. With its GMP quality assurance and long history of being packaged by a family-owned company, you can trust the quality of this supplement.

What We Like
High count of active organisms
Easy to swallow capsules
Affordable price point
No weird aroma
Does not upset stomach
What We Don't Like
Refrigeration requirement
Shipping issues with temperature
#TOP 3

NOW Supplements Probiotic Capsules

2932
White
NOW Supplements Probiotic Capsules Cover
NOW Foods Supplements, 8 Billion Acidophilus & Bifidus, Dairy, Soy and Gluten Free, Strain Verified, 120 Veg Capsules
ftb score rating icon9.6
FTB Score

These probiotic capsules promote positive probiotic balance and healthy intestinal flora. The blend of prominent types of resident intestinal bacteria has a potency of 8 billion CFU through the Best By date. The probiotic strains are identity-verified using DNA-fingerprinting technology. The product has NPA A-rated GMP certification and is packaged in the USA by a family-owned company. Refrigeration is required to maintain potency.

What We Like
Effective for digestive issues
Reliable NOW brand
Easy on stomach
Good quantity for price
Helps restore gut flora
What We Don't Like
Received old product
Doubt about effectiveness
#TOP 4

Vitamatic Acidophilus Probiotic Supplement

810078474067
Vitamatic Acidophilus Probiotic Supplement Cover
Vitamatic Acidophilus Probiotic - 10 Billion CFU - 5X Potency - Daily Probiotic Supplement, Supports Digestive Health - 120 Tablets
ftb score rating icon9.6
FTB Score

The Vitamatic Probiotic Supplement contains 10 billion CFUs of Lactobacillus acidophilus, which is essential for maintaining a healthy gut and immune system. By supporting the balance of gut bacteria, this supplement enhances your digestive health and promotes overall well-being. It's designed for convenience, with a simple once-daily tablet that's gluten-free, vegan, and non-GMO. You won’t find any artificial additives here, making it a clean choice for your daily routine. Manufactured in a certified facility in the USA, you can trust its quality and potency.

What We Like
Effective for daily meals
Great price
Better than gummies
Small pill size
Home delivery available
What We Don't Like
Not as effective as other brands
Insufficient use for full evaluation
#TOP 5

21st Century Acidophilus Capsules, 100 Count (21339)

21st Century Acidophilus Capsules, 100 Count (21339) Cover
21st Century Acidophilus Capsules, 100 Count (21339)
ftb score rating icon9.4
FTB Score

The 21st Century Acidophilus Capsules are a great choice for anyone looking to support healthy digestion and optimal nutrition. These probiotic capsules are designed to aid in the maintenance of probiotic activity in the intestine, making them a great addition to any diet. Please note that this product is not intended to diagnose, treat, cure, or prevent any disease. During the summer months, the product may arrive warm, but Amazon follows the manufacturer's recommendations when storing and shipping products.

What We Like
Effective for gut health
Easy-to-swallow pills
Non-refrigerated storage
Good price and availability
Fast service
#TOP 6

Nature's Way Probiotic Pearls Acidophilus for Digestive Health

Nature's Way Probiotic Pearls Acidophilus for Digestive Health Cover
Nature's Way Acidophilus Probiotic Pearls, Supports Digestive Balance and Gut Health*, Protects Against Occasional Constipation and Bloating*, 1 Billion Live Cultures, 90 Softgels (Packaging May Vary)
ftb score rating icon9.3
FTB Score

Nature's Way Probiotic Pearls Acidophilus is a daily probiotic formula that contains 2 strains and 1 billion cultures in a convenient, once-daily softgel. It helps protect against occasional bloating, constipation, and digestive discomfort while promoting digestive balance, immune, and colon health. The small probiotic pearls are easy to swallow and perfect for taking anywhere and everywhere, with no refrigeration required.

What We Like
Easy to swallow pearls
No refrigeration needed
Supports digestive balance
Promotes immune health
Effective for gut health
What We Don't Like
Initial adjustment period
#TOP 7

Natural Foundation Probiotic Tablets

Natural Foundation Probiotic Tablets Cover
Lactobacillus Acidophilus Probiotic Supplement 240 Tablets 3 Billion CFU Probiotics for Men & Women Supports Intestinal Digestive & Gut Health Made in The USA (240, Lactobacillus Acidophilus)
ftb score rating icon9.2
FTB Score

Natural Foundation Probiotics are designed to support your digestive health. Each tablet provides a potent dose of 3 billion CFU of beneficial probiotics, helping to promote a balanced gut flora. With 240 tablets in a convenient bottle, you can easily incorporate them into your daily routine. The recommended serving of two tablets makes it simple to maintain your gut health. This supplement is suitable for both men and women, ensuring that everyone can benefit from improved intestinal function.

What We Like
Effective for digestion
Improves sleep quality
Supports weight loss
Good price and quality
Tiny pill size
What We Don't Like
Chalky taste
Uncoated pills
#TOP 8

Carlyle Acidophilus Probiotic

CL4475
Carlyle Acidophilus Probiotic Cover
Carlyle Acidophilus Probiotic Capsules for Women and Men | 500 Million CFU | 200 Pills | Lactobacillus Supplement | Non-GMO and Gluten Free
ftb score rating icon9.1
FTB Score

Carlyle Acidophilus Probiotic is a premium supplement that provides maximum daily support for your overall well-being. With 500 million active organisms per serving, this probiotic is designed to promote a healthy digestive system. The quick release capsules make it easy to incorporate into your daily routine, ensuring convenience and consistency. Carlyle is a trusted brand that is committed to your wellness, offering superior quality products that are laboratory tested and made with trusted ingredients. With Carlyle Acidophilus Probiotic, you can enjoy the benefits of a gluten-free, non-GMO formula that is naturally free of artificial color, artificial sweetener, and preservatives. Take control of your health with Carlyle Probiotic.

What We Like
Effective for gut bacteria
Great value for quantity
Cost-effective compared to brands
Quality product
What We Don't Like
Results not yet fully determined
#TOP 9

American Health Daily Chewable Tablet Acidophilus, 60 Count

American Health Daily Chewable Tablet Acidophilus, 60 Count Cover
AMERICAN HEALTH Daily Chewable Tablet Acidophilus, 1 Billion Live Cultures, Beneficial Bacteria for The Digestive & Immune Systems, Strawberry, 60 Count
ftb score rating icon8.9
FTB Score

American Health Daily Chewable Tablet Acidophilus is formulated with Acidophilus, which is a friendly bacteria for the digestive & immune systems. It contains a mix of two probiotic strains - Lactobacillus acidophilus La-14 and Bifidobacterium lactis Bi-04, delivering 1 billion microorganisms to the GI tract. Suitable for adults and children ages 4 and up, the kid-friendly, easy, and convenient chewable form makes these probiotic supplements easy to take at any time. The product comes in a delicious, strawberry-flavored chewable wafer, and Innovative packaging guarantees probiotic potency through expiration.

What We Like
Great taste
Effective for digestion
Clean ingredients
Consistent results
Easy to take
What We Don't Like
Pills broken in bottle
#TOP 10

Now Foods Acidophilus 2 Billion 250 Caps

733739029072
1 Count (Pack of 1)
Now Foods Acidophilus 2 Billion 250 Caps Cover
Now Foods Acidophilus 2 Billion 250 Caps
ftb score rating icon8.7
FTB Score

This Acidophilus supplement contains 2 billion CFU of probiotics in each capsule to support digestive health. The 250 capsule bottle ensures a longer supply of the supplement. It is a Now Foods product, which guarantees high-quality standards.

What We Like
Effective gut health support
Easy to swallow capsules
Good value for money
Recommended by healthcare professionals
Beneficial for pets
What We Don't Like
Incorrect quantity received
Buying Guide Image

Tips for Choosing the Acidophilus Supplements

What is Acidophilus?

Acidophilus is a type of beneficial bacteria that resides in the digestive system. It is part of the lactic acid bacteria family, which is known for its ability to produce lactic acid. This lactic acid helps to maintain the balance of good and bad bacteria in the gut, which is essential for overall health and wellness.

Why Take Acidophilus Supplements?

While acidophilus is naturally present in the body, there are several reasons why you may want to consider taking an acidophilus supplement. For one, the number of acidophilus bacteria in the body can be reduced due to factors such as stress, illness, and certain medications. Additionally, the modern diet, which is often high in processed and sugary foods, can also reduce the levels of acidophilus in the body.

Taking an acidophilus supplement can help to restore the balance of good bacteria in the gut, which can support a healthy digestive system. Acidophilus supplements can also help to support the immune system and may even have a positive effect on overall health and wellbeing.

Choosing an Acidophilus Supplement

When it comes to choosing an acidophilus supplement, there are a few things to consider. First, it's important to choose a supplement that contains a high number of live bacteria. This is because the beneficial effects of acidophilus are dependent on the number of live bacteria present in the supplement.

Another factor to consider is the type of bacteria used in the supplement. Some supplements use a single strain of acidophilus bacteria, while others use a blend of multiple strains. While there is no clear consensus on which is better, some research suggests that a blend of multiple strains may be more effective at supporting gut health.

It's also important to choose an acidophilus supplement that is manufactured using high-quality standards. Look for supplements that are made using GMP (Good Manufacturing Practices) and are third-party tested for quality and purity.

Finally, consider the form of the supplement. Acidophilus supplements are available in a variety of forms, including capsules, tablets, powders, and liquids. Some people may prefer one form over another, so it's a good idea to experiment to find the one that works best for you.

Conclusion

Acidophilus supplements can be a great way to support a healthy digestive system and maintain the balance of good bacteria in the gut. When choosing an acidophilus supplement, look for a product that contains a high number of live bacteria, is made using high-quality standards, and comes in a form that is convenient for you to take. With so many options available, you're sure to find an acidophilus supplement that meets your needs.

Frequently Asked Questions (FAQs)

1. What are the benefits of taking acidophilus?

Taking acidophilus as a supplement or consuming it through certain foods like yogurt can provide several benefits. Acidophilus is commonly used to treat vaginal inflammation (bacterial vaginosis) and digestive disorders. It also promotes the growth of good bacteria in the body.

2. Is it OK to take acidophilus daily?

In general, taking acidophilus daily is considered safe for most individuals. However, some people may experience side effects like gas, upset stomach, and diarrhea when taking more than 1 to 2 billion L. acidophilus CFUs daily. It's important to consult with a healthcare professional before starting any new supplement regimen.

3. Is it better to take acidophilus or probiotics?

Acidophilus is a type of probiotic that offers specific benefits. Studies suggest that L. acidophilus may be more effective than other types of probiotics in reducing cholesterol levels. However, the choice between acidophilus and other probiotics depends on individual needs and health conditions.

4. When should I take acidophilus probiotics?

To improve the survival rates of probiotics through stomach acid, it's recommended to take them on an empty stomach. Many people take acidophilus probiotics first thing in the morning, about 30 minutes before breakfast, or 2-3 hours after the last meal in the evening. Consistency in timing is key.

5. Does acidophilus help with belly fat?

In a study, the combination of Lactobacillus acidophilus with other strains and a healthy diet resulted in reduced polyunsaturated fatty acids and a slimmer waist circumference in women. However, it's important to note that individual results may vary and a comprehensive approach to weight management is recommended.

6. How long does it take for acidophilus to work?

If you are taking a high-quality, multispecies, and multistrain acidophilus supplement, you may notice initial improvements in digestion and health benefits within the first 1-2 weeks. Individual sensitivity may vary, and some people may experience a difference in just a few days.

7. When should you not take acidophilus?

If you develop signs of an infection such as fever or chills, it's important to stop taking acidophilus and seek immediate medical guidance. Additionally, if you experience signs of a serious allergic reaction, such as rash, swelling, or trouble breathing, it's recommended to discontinue use and seek medical attention.

8. Are there any side effects from taking acidophilus?

While rare, a serious allergic reaction to acidophilus can occur. If you notice symptoms like rash, itching, swelling (especially of the face, tongue, or throat), dizziness, or trouble breathing, it's important to seek medical help immediately. This is not an exhaustive list of possible side effects, and it's advisable to consult a healthcare professional.

9. What naturally kills bad bacteria in the gut?

To address bad bacteria in the gut, several strategies can be employed. These include adopting an anti-inflammatory diet, engaging in regular exercise, prioritizing good quality sleep, and incorporating probiotics into the routine. These measures can help promote a healthy balance of bacteria in the gut before considering antimicrobials or antibiotics.

Editor's Notes

During our acidophilus supplement research, we found 24 acidophilus supplement products and shortlisted 10 quality products. We collected and analyzed 349,390 customer reviews through our big data system to write the acidophilus supplements list. We found that most customers choose acidophilus supplements with an average price of $15.57.

The acidophilus supplements are available for purchase. We have researched hundreds of brands and picked the top brands of acidophilus supplements, including Nature's Bounty, NOW Foods, Vitamatic, 21st Century, Nature's Way. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

Acidophilus Supplements Comparison Table

#TOP1
Nature’s Bounty Acidophilus Probiotic Cover
#TOP2
NOW Acidophilus Two Billion Cover
#TOP3
NOW Supplements Probiotic Capsules Cover
#TOP4
Vitamatic Acidophilus Probiotic Supplement Cover
#TOP5
21st Century Acidophilus Capsules, 100 Count (21339) Cover
#TOP6
Nature's Way Probiotic Pearls Acidophilus for Digestive Health Cover
#TOP7
Natural Foundation Probiotic Tablets Cover
#TOP8
Carlyle Acidophilus Probiotic Cover
#TOP9
American Health Daily Chewable Tablet Acidophilus, 60 Count Cover
#TOP10
Now Foods Acidophilus 2 Billion 250 Caps Cover
BrandNature's BountyNOW FoodsNOW FoodsVitamatic21st CenturyNature's WayNatural Foundation SupplementsCarlyleAmerican HealthNOW Foods
Unit Count200 Count100 Count120 Count120.00 Count100 Count90 Count240 Count200.00 Count60 Count1 Count
Item FormTabletCapsuleCapsuleTabletCapsuleSoftgelTabletCapsuleCapsuleCapsule
FlavorUnflavoredUnflavoredUnflavoredUnflavoredUnflavouredUnflavoredLactobacillus Acidophilus-StrawberryApple
Product BenefitsDigestive Health SupportDigestive Health SupportImmune SupportDigestive Health SupportImmune Support, Digestive Health Support, Stomach Health SupportNutritional SupportDigestive Health Support-Immune Support, Digestive Health SupportSupport
Item Weight0.2 Pounds0.06 Kilograms0.15 Pounds--0.02 Kilograms50 Grams0.12 Kilograms0.11 Kilograms2.4 Ounces
Item dimensions L x W x H1.97 x 3.94 x 4.07 inches1.95 x 1.95 x 4.3 inches2.15 x 2.1 x 4.1 inches-9.4 x 6.4 x 4.6 inches1.6 x 4.3 x 4.7 inches-2.5 x 2.5 x 4.5 inches2.2 x 2.2 x 4 inches2 x 2 x 4 inches
Primary Supplement TypeProbioticProbioticProbioticAcidophullus SupplementAciddophilusProbiotic--Probiotic-
Age Range (Description)-Adult-AdultAll StagesAdultAdultAdultAdult-
Special IngredientsAcidophilus-AcidophilusAcidophilusAcidophilus, Gluten FreeProbiotic----
Diet TypeGluten FreeVeganGluten Free, Vegan-Gluten Free---Vegan-
FTB Score
ftb score rating icon9.9
ftb score rating icon9.8
ftb score rating icon9.6
ftb score rating icon9.6
ftb score rating icon9.4
ftb score rating icon9.3
ftb score rating icon9.2
ftb score rating icon9.1
ftb score rating icon8.9
ftb score rating icon8.7
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